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Links between transforming growth factor-β and canonical Wnt signaling yield new insights into breast cancer susceptibility, suppression and tumor heterogeneity

In a recent issue of Breast Cancer Research, investigators from the Serra laboratory describe a novel mechanism of transforming growth factor (TGF)-β tumor suppression. Previously, the authors discovered that stromal TGF-β signaled through Wnt5a to restrain pubertal ductal elongation and branching....

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Detalles Bibliográficos
Autores principales: Incassati, Angela, Pinderhughes, Alicia, Eelkema, Rachel, Cowin, Pamela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716492/
https://www.ncbi.nlm.nih.gov/pubmed/19519951
http://dx.doi.org/10.1186/bcr2253