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Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

INTRODUCTION: Endothelin (EDN) signalling plays a crucial role in cell differentiation, proliferation and migration processes. There is compelling evidence that altered EDN signalling is involved in carcinogenesis by modulating cell survival and promoting invasiveness. To date, most reports have foc...

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Detalles Bibliográficos
Autores principales: Wiesmann, Frank, Veeck, Jürgen, Galm, Oliver, Hartmann, Arndt, Esteller, Manel, Knüchel, Ruth, Dahl, Edgar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716502/
https://www.ncbi.nlm.nih.gov/pubmed/19527488
http://dx.doi.org/10.1186/bcr2319