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Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer
INTRODUCTION: Inhibitor of apoptosis (IAPs) proteins are a family of proteins that can block apoptosis in normal cells and have been suggested to cause resistance to apoptosis in cancer. Overexpression of oncogenic receptor tyrosine kinases is common in breast cancer; in particular 20% of all cases...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716510/ https://www.ncbi.nlm.nih.gov/pubmed/19563669 http://dx.doi.org/10.1186/bcr2328 |