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Blocking TLR2 Activity Attenuates Pulmonary Metastases of Tumor

BACKGROUND: Metastasis is the most pivotal cause of mortality in cancer patients. Immune tolerance plays a crucial role in tumor progression and metastasis. METHODS AND FINDINGS: In this study, we investigated the potential roles and mechanisms of TLR2 signaling on tumor metastasis in a mouse model...

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Detalles Bibliográficos
Autores principales: Yang, Hong-Zhen, Cui, Bing, Liu, Han-Zhi, Mi, Su, Yan, Jun, Yan, Hui-Min, Hua, Fang, Lin, Heng, Cai, Wen-Feng, Xie, Wen-Jie, Lv, Xiao-Xi, Wang, Xiao-Xing, Xin, Bing-Mu, Zhan, Qi-Min, Hu, Zhuo-Wei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716531/
https://www.ncbi.nlm.nih.gov/pubmed/19654875
http://dx.doi.org/10.1371/journal.pone.0006520