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Association between Protective and Deleterious HLA Alleles with Multiple Sclerosis in Central East Sardinia

The human leukocyte antigen (HLA) complex on chromosome 6p21 has been unambiguously associated with multiple sclerosis (MS). The complex features of the HLA region, especially its high genic content, extreme polymorphism, and extensive linkage disequilibrium, has prevented to resolve the nature of H...

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Detalles Bibliográficos
Autores principales: Pastorino, Roberta, Menni, Cristina, Barca, Monserrata, Foco, Luisa, Saddi, Valeria, Gazzaniga, Giovanna, Ferrai, Raffaela, Mascaretti, Luca, Dudbridge, Frank, Berzuini, Carlo, Murgia, Salvatore Bruno, Piras, Maria Luisa, Ticca, Anna, Bitti, Pier Paolo, Bernardinelli, Luisa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716537/
https://www.ncbi.nlm.nih.gov/pubmed/19654877
http://dx.doi.org/10.1371/journal.pone.0006526