The WAVE Regulatory Complex is Inhibited

The WAVE Regulatory Complex (WRC) transmits information from the Rac GTPase to the actin nucleator, Arp2/3 complex. We have reconstituted recombinant human and Drosophila WRC in several forms and shown that they are inactive toward Arp2/3 complex, but can be activated by Rac in nucleotide dependent...

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Detalles Bibliográficos
Autores principales: Ismail, Ayman M., Padrick, Shae B., Chen, Baoyu, Umetani, Junko, Rosen, Michael K.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716658/
https://www.ncbi.nlm.nih.gov/pubmed/19363480
http://dx.doi.org/10.1038/nsmb.1587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716658/
https://www.ncbi.nlm.nih.gov/pubmed/19363480
http://dx.doi.org/10.1038/nsmb.1587

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