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TNF-α mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations

PURPOSE: The pathophysiology of diabetic retinopathy involves leukocyte adhesion to retinal vasculature, early blood-retinal barrier breakdown, capillary nonperfusion, and endothelial cell death. We investigated the involvement of tumor necrosis factor α (TNF-α) in diabetes-related histopathological...

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Detalles Bibliográficos
Autores principales: Joussen, Antonia M., Doehmen, Sven, Le, Minh L., Koizumi, Kan, Radetzky, Sven, Krohne, Tim U., Poulaki, Vassiliki, Semkova, Irina, Kociok, Norbert
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716944/
https://www.ncbi.nlm.nih.gov/pubmed/19641635