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TNF-α mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations
PURPOSE: The pathophysiology of diabetic retinopathy involves leukocyte adhesion to retinal vasculature, early blood-retinal barrier breakdown, capillary nonperfusion, and endothelial cell death. We investigated the involvement of tumor necrosis factor α (TNF-α) in diabetes-related histopathological...
Autores principales: | Joussen, Antonia M., Doehmen, Sven, Le, Minh L., Koizumi, Kan, Radetzky, Sven, Krohne, Tim U., Poulaki, Vassiliki, Semkova, Irina, Kociok, Norbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716944/ https://www.ncbi.nlm.nih.gov/pubmed/19641635 |
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