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Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system

BACKGROUND: (+)-Nootkatone (4) is a high added-value compound found in grapefruit juice. Allylic oxidation of the sesquiterpene (+)-valencene (1) provides an attractive route to this sought-after flavoring. So far, chemical methods to produce (+)-nootkatone (4) from (+)-valencene (1) involve unsafe...

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Detalles Bibliográficos
Autores principales: Girhard, Marco, Machida, Kazuhiro, Itoh, Masashi, Schmid, Rolf D, Arisawa, Akira, Urlacher, Vlada B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717049/
https://www.ncbi.nlm.nih.gov/pubmed/19591681
http://dx.doi.org/10.1186/1475-2859-8-36