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Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system
BACKGROUND: (+)-Nootkatone (4) is a high added-value compound found in grapefruit juice. Allylic oxidation of the sesquiterpene (+)-valencene (1) provides an attractive route to this sought-after flavoring. So far, chemical methods to produce (+)-nootkatone (4) from (+)-valencene (1) involve unsafe...
Autores principales: | Girhard, Marco, Machida, Kazuhiro, Itoh, Masashi, Schmid, Rolf D, Arisawa, Akira, Urlacher, Vlada B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717049/ https://www.ncbi.nlm.nih.gov/pubmed/19591681 http://dx.doi.org/10.1186/1475-2859-8-36 |
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