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The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development

BACKGROUND: SH3 containing Lymphocyte Protein (SLY1) is a putative adapter protein exclusively expressed in lymphocytes which is involved in antigen receptor induced activation. We previously have generated SLY1(Δ/Δ )mice harbouring a partial deletion in the N-terminal region of SLY1 which revealed...

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Detalles Bibliográficos
Autores principales: Reis, Bernhard, Pfeffer, Klaus, Beer-Hammer, Sandra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717057/
https://www.ncbi.nlm.nih.gov/pubmed/19604361
http://dx.doi.org/10.1186/1471-2172-10-38