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A novel Poly(ε-caprolactone)-Pluronic-Poly(ε-caprolactone) grafted Polyethyleneimine(PCFC-g-PEI), Part 1, synthesis, cytotoxicity, and in vitro transfection study

BACKGROUND: Polyethyleneimine (PEI), a cationic polymer, is one of the successful and widely used vectors for non-viral gene transfection in vitro. However, its in vivo application was greatly limited due to its high cytotoxicity and short duration of gene expression. To improve its biocompatibility...

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Detalles Bibliográficos
Autores principales: Shi, Shuai, Guo, QingFa, Kan, Bing, Fu, ShaoZhi, Wang, XiuHong, Gong, ChangYang, Deng, HongXin, Luo, Feng, Zhao, Xia, Wei, YuQuan, Qian, ZhiYong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717081/
https://www.ncbi.nlm.nih.gov/pubmed/19607728
http://dx.doi.org/10.1186/1472-6750-9-65