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Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis

BACKGROUND: Clinical trials where cancer patients were treated with protease inhibitors have suggested that the serine protease, prostasin, may act as a tumour suppressor. Prostasin is proteolytically activated by the serine protease, matriptase, which has a very high oncogenic potential. Prostasin...

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Detalles Bibliográficos
Autores principales: Selzer-Plon, Joanna, Bornholdt, Jette, Friis, Stine, Bisgaard, Hanne C, Lothe, Inger MB, Tveit, Kjell M, Kure, Elin H, Vogel, Ulla, Vogel, Lotte K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717118/
https://www.ncbi.nlm.nih.gov/pubmed/19555470
http://dx.doi.org/10.1186/1471-2407-9-201