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Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

BACKGROUND: Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlated with adverse patient survival in cancer, we aimed at investigating a potentia...

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Detalles Bibliográficos
Autores principales: Veeck, Jürgen, Wild, Peter J, Fuchs, Thomas, Schüffler, Peter J, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717119/
https://www.ncbi.nlm.nih.gov/pubmed/19570204
http://dx.doi.org/10.1186/1471-2407-9-217