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Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA and PKG via a Membrane G-Protein–Coupled Estrogen Receptor

BACKGROUND: Fetal exposure to environmental estrogens may contribute to hypofertility and/or to testicular germ cell cancer. However, many of these xenoestrogens have only a weak affinity for the classical estrogen receptors (ERs,) which is 1,000-fold less potent than the affinity of 17β-estradiol (...

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Detalles Bibliográficos
Autores principales: Bouskine, Adil, Nebout, Marielle, Brücker-Davis, Françoise, Benahmed, Mohamed, Fenichel, Patrick
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717129/
https://www.ncbi.nlm.nih.gov/pubmed/19654912
http://dx.doi.org/10.1289/ehp.0800367