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Distinct Contributions of JNK and p38 to Chromium Cytotoxicity and Inhibition of Murine Embryonic Stem Cell Differentiation

BACKGROUND: Potassium dichromate [Cr(VI)] is a widespread environmental toxicant responsible for increased risk of several human diseases. Cr(VI) exposure leads to activation of mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK)1/2, p38, and extracellular-signal regul...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Ovesen, Jerald L., Puga, Alvaro, Xia, Ying
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717140/
https://www.ncbi.nlm.nih.gov/pubmed/19654923
http://dx.doi.org/10.1289/ehp.0800157