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Distinct Contributions of JNK and p38 to Chromium Cytotoxicity and Inhibition of Murine Embryonic Stem Cell Differentiation
BACKGROUND: Potassium dichromate [Cr(VI)] is a widespread environmental toxicant responsible for increased risk of several human diseases. Cr(VI) exposure leads to activation of mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK)1/2, p38, and extracellular-signal regul...
Autores principales: | Chen, Liang, Ovesen, Jerald L., Puga, Alvaro, Xia, Ying |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717140/ https://www.ncbi.nlm.nih.gov/pubmed/19654923 http://dx.doi.org/10.1289/ehp.0800157 |
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