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HIV-1 Matrix Dependent Membrane Targeting Is Regulated by Gag mRNA Trafficking

Retroviral Gag polyproteins are necessary and sufficient for virus budding. Productive HIV-1 Gag assembly takes place at the plasma membrane. However, little is known about the mechanisms by which thousands of Gag molecules are targeted to the plasma membrane. Using a bimolecular fluorescence comple...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Sturgeon, Timothy, Weisz, Ora A., Mothes, Walther, Montelaro, Ronald C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717210/
https://www.ncbi.nlm.nih.gov/pubmed/19662089
http://dx.doi.org/10.1371/journal.pone.0006551