Lack of Association between Genetic Polymorphisms in Enzymes Associated with Folate Metabolism and Unexplained Reduced Sperm Counts

BACKGROUND: The metabolic pathway of folate is thought to influence DNA stability either by inducing single/double stranded breaks or by producing low levels of S-adenosyl-methionine leading to abnormal gene expression and chromosome segregation. Polymorphisms in the genes encoding enzymes in the fo...

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Detalles Bibliográficos
Autores principales: Ravel, Celia, Chantot-Bastaraud, Sandra, Chalmey, Clementine, Barreiro, Luis, Aknin-Seifer, Isabelle, Pfeffer, Jerome, Berthaut, Isabelle, Mathieu, E. Emmanuelle, Mandelbaum, Jacqueline, Siffroi, Jean-Pierre, McElreavey, Ken, Bashamboo, Anu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717325/
https://www.ncbi.nlm.nih.gov/pubmed/19657388
http://dx.doi.org/10.1371/journal.pone.0006540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717325/
https://www.ncbi.nlm.nih.gov/pubmed/19657388
http://dx.doi.org/10.1371/journal.pone.0006540

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