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Inhibition of Aldose Reductase Prevents Experimental Allergic Airway Inflammation in Mice

BACKGROUND: The bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequent airway hyper-responsiveness, is a leading cause of morbidity and mortality in critically ill patients. Several studies have shown that oxidative stress plays a key role in initiation as...

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Detalles Bibliográficos
Autores principales: Yadav, Umesh C. S., Ramana, Kota V., Aguilera-Aguirre, Leopoldo, Boldogh, Istvan, Boulares, Hamid A., Srivastava, Satish K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717330/
https://www.ncbi.nlm.nih.gov/pubmed/19657391
http://dx.doi.org/10.1371/journal.pone.0006535