Cargando…
Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents
PURPOSE: The purpose of this investigation was to synthesize a series of carbonate and carbamate derivatives of 4-demethylpenclomedine (DM-PEN), the major plasma non-toxic metabolite of penclomedine (PEN) seen in patients. DM-PEN has been observed to be an active antitumor agent in mouse human xenog...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717391/ https://www.ncbi.nlm.nih.gov/pubmed/19255760 http://dx.doi.org/10.1007/s00280-009-0933-9 |