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p,p′-DDE Induces Apoptosis of Rat Sertoli Cells via a FasL-Dependent Pathway

One,1-dichloro-2,2 bis(p-chlorophenyl) ethylene (p,p′-DDE), the major metabolite of 2,2-bis(4-Chlorophenyl)-1,1,1-trichloroethane (DDT), is a known persistent organic pollutant and male reproductive toxicant. It has antiandrogenic effect. However, the mechanism by which p,p′-DDE exposure causes male...

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Detalles Bibliográficos
Autores principales: Shi, Yuqin, Song, Yang, Wang, Yinan, Liang, Xianmin, Hu, Yafei, Guan, Xia, Cheng, Jin, Yang, Kedi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717566/
https://www.ncbi.nlm.nih.gov/pubmed/19644561
http://dx.doi.org/10.1155/2009/181282