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Activity of the β-catenin phosphodestruction complex at cell–cell contacts is enhanced by cadherin-based adhesion
It is well established that cadherin protein levels impact canonical Wnt signaling through binding and sequestering β-catenin (β-cat) from T-cell factor family transcription factors. Whether changes in intercellular adhesion can affect β-cat signaling and the mechanism through which this occurs has...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717642/ https://www.ncbi.nlm.nih.gov/pubmed/19620634 http://dx.doi.org/10.1083/jcb.200811108 |