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Application of rate-equilibrium free energy relationship analysis to nonequilibrium ion channel gating mechanisms
Rate-equilibrium free energy relationship (REFER) analysis provides information on transition-state structures and has been applied to reveal the temporal sequence in which the different regions of an ion channel protein move during a closed–open conformational transition. To date, the theory used t...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717696/ https://www.ncbi.nlm.nih.gov/pubmed/19635854 http://dx.doi.org/10.1085/jgp.200910268 |