Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct(,)

[Image: see text] Oxidative stress can induce the formation of reactive electrophiles, such as DNA peroxidation products, e.g., base propenals, and lipid peroxidation products, e.g., malondialdehyde. Base propenals and malondialdehyde react with DNA to form adducts, including 3-(2′-deoxy-β-d-erythro...

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Detalles Bibliográficos
Autores principales: Eoff, Robert L., Stafford, Jennifer B., Szekely, Jozsef, Rizzo, Carmelo J., Egli, Martin, Guengerich, F. Peter, Marnett, Lawrence J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717710/
https://www.ncbi.nlm.nih.gov/pubmed/19492857
http://dx.doi.org/10.1021/bi9003588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717710/
https://www.ncbi.nlm.nih.gov/pubmed/19492857
http://dx.doi.org/10.1021/bi9003588

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