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Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct(,)
[Image: see text] Oxidative stress can induce the formation of reactive electrophiles, such as DNA peroxidation products, e.g., base propenals, and lipid peroxidation products, e.g., malondialdehyde. Base propenals and malondialdehyde react with DNA to form adducts, including 3-(2′-deoxy-β-d-erythro...
Autores principales: | Eoff, Robert L., Stafford, Jennifer B., Szekely, Jozsef, Rizzo, Carmelo J., Egli, Martin, Guengerich, F. Peter, Marnett, Lawrence J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717710/ https://www.ncbi.nlm.nih.gov/pubmed/19492857 http://dx.doi.org/10.1021/bi9003588 |
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