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Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)

BACKGROUND: Metabolic perturbations arising from malignant transformation have not been systematically characterized in human lung cancers in situ. Stable isotope resolved metabolomic analysis (SIRM) enables functional analysis of gene dysregulations in lung cancer. To this purpose, metabolic change...

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Detalles Bibliográficos
Autores principales: Fan, Teresa WM, Lane, Andrew N, Higashi, Richard M, Farag, Mohamed A, Gao, Hong, Bousamra, Michael, Miller, Donald M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717907/
https://www.ncbi.nlm.nih.gov/pubmed/19558692
http://dx.doi.org/10.1186/1476-4598-8-41