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Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12

Macrophages in the central nervous system (CNS) and other tissues are an important cellular reservoir for human immunodeficiency virus type 1 (HIV) infection, particularly in the later stages of disease. Macrophage-tropic HIV strains have an enhanced capacity to enter cells expressing low levels of...

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Detalles Bibliográficos
Autores principales: Dunfee, Rebecca L, Thomas, Elaine R, Gabuzda, Dana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717910/
https://www.ncbi.nlm.nih.gov/pubmed/19619305
http://dx.doi.org/10.1186/1742-4690-6-69