Developing a scalable model of recombinant protein yield from Pichia pastoris: the influence of culture conditions, biomass and induction regime

BACKGROUND: The optimisation and scale-up of process conditions leading to high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences. Typical experiments rely on varying selected parameters through repeated rounds of trial-and-error optimisation. To rationalise this,...

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Detalles Bibliográficos
Autores principales: Holmes, William J, Darby, Richard AJ, Wilks, Martin DB, Smith, Rodney, Bill, Roslyn M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717918/
https://www.ncbi.nlm.nih.gov/pubmed/19570229
http://dx.doi.org/10.1186/1475-2859-8-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717918/
https://www.ncbi.nlm.nih.gov/pubmed/19570229
http://dx.doi.org/10.1186/1475-2859-8-35

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