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Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions

BACKGROUND: Understanding how individual genes contribute towards the fitness of an organism is a fundamental problem in biology. Although recent genome-wide screens have generated abundant data on quantitative fitness for single gene knockouts, very few studies have systematically integrated other...

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Detalles Bibliográficos
Autores principales: Pache, Roland A, Babu, M Madan, Aloy, Patrick
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717920/
https://www.ncbi.nlm.nih.gov/pubmed/19615085
http://dx.doi.org/10.1186/1752-0509-3-74