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Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions
BACKGROUND: Understanding how individual genes contribute towards the fitness of an organism is a fundamental problem in biology. Although recent genome-wide screens have generated abundant data on quantitative fitness for single gene knockouts, very few studies have systematically integrated other...
Autores principales: | Pache, Roland A, Babu, M Madan, Aloy, Patrick |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717920/ https://www.ncbi.nlm.nih.gov/pubmed/19615085 http://dx.doi.org/10.1186/1752-0509-3-74 |
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