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Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans

BACKGROUND: There is evidence from animal studies that serotonin (5-HT) can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on individual variability in response to opioid treatment of...

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Detalles Bibliográficos
Autores principales: Kosek, Eva, Jensen, Karin B, Lonsdorf, Tina B, Schalling, Martin, Ingvar, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717925/
https://www.ncbi.nlm.nih.gov/pubmed/19570226
http://dx.doi.org/10.1186/1744-8069-5-37