Extensive sequence turnover of the signal peptides of members of the GDF/BMP family: exploring their evolutionary landscape

We show that the predicted signal peptide (SP) sequences of the secreted factors GDF9, BMP15 and AMH are well conserved in mammals but dramatic divergence is noticed for more distant orthologs. Interestingly, bioinformatic predictions show that the divergent protein segments do encode SPs. Thus, suc...

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Detalles Bibliográficos
Autores principales: Veitia, Reiner A, Caburet, Sandrine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Discovery Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717928/
https://www.ncbi.nlm.nih.gov/pubmed/19607682
http://dx.doi.org/10.1186/1745-6150-4-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717928/
https://www.ncbi.nlm.nih.gov/pubmed/19607682
http://dx.doi.org/10.1186/1745-6150-4-22

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