Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...

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Detalles Bibliográficos
Autores principales: Comincini, Sergio, Paolillo, Mayra, Barbieri, Giulia, Palumbo, Silvia, Sbalchiero, Elena, Azzalin, Alberto, Russo, Marika A., Schinelli, Sergio
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Methodology Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718324/
https://www.ncbi.nlm.nih.gov/pubmed/19657395
http://dx.doi.org/10.1155/2009/924565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718324/
https://www.ncbi.nlm.nih.gov/pubmed/19657395
http://dx.doi.org/10.1155/2009/924565

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