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Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens
In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...
Autores principales: | Comincini, Sergio, Paolillo, Mayra, Barbieri, Giulia, Palumbo, Silvia, Sbalchiero, Elena, Azzalin, Alberto, Russo, Marika A., Schinelli, Sergio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718324/ https://www.ncbi.nlm.nih.gov/pubmed/19657395 http://dx.doi.org/10.1155/2009/924565 |
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