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Multisite Phosphorylation of the Guanine Nucleotide Exchange Factor Cdc24 during Yeast Cell Polarization

BACKGROUND: Cell polarization is essential for processes such as cell migration and asymmetric cell division. A common regulator of cell polarization in most eukaryotic cells is the conserved Rho GTPase, Cdc42. In budding yeast, Cdc42 is activated by a single guanine nucleotide exchange factor, Cdc2...

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Detalles Bibliográficos
Autores principales: Wai, Stephanie C., Gerber, Scott A., Li, Rong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718613/
https://www.ncbi.nlm.nih.gov/pubmed/19668330
http://dx.doi.org/10.1371/journal.pone.0006563