Deleted in Liver Cancer 2 (DLC2) Was Dispensable for Development and Its Deficiency Did Not Aggravate Hepatocarcinogenesis

DLC2 (deleted in liver cancer 2), a Rho GTPase-activating protein, was previously shown to be underexpressed in human hepatocellular carcinoma and has tumor suppressor functions in cell culture models. We generated DLC2-deficient mice to investigate the tumor suppressor role of DLC2 in hepatocarcino...

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Detalles Bibliográficos
Autores principales: Yau, Tai On, Leung, Thomas Ho Yin, Lam, Sandra, Cheung, Oi Fung, Tung, Edmund Kwok Kwan, Khong, Pek Lan, Lam, Amy, Chung, Sookja, Ng, Irene Oi Lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718616/
https://www.ncbi.nlm.nih.gov/pubmed/19668331
http://dx.doi.org/10.1371/journal.pone.0006566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718616/
https://www.ncbi.nlm.nih.gov/pubmed/19668331
http://dx.doi.org/10.1371/journal.pone.0006566

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