Cargando…

Predicting protein thermostability changes from sequence upon multiple mutations

Motivation: A basic question in protein science is to which extent mutations affect protein thermostability. This knowledge would be particularly relevant for engineering thermostable enzymes. In several experimental approaches, this issue has been serendipitously addressed. It would be therefore co...

Descripción completa

Detalles Bibliográficos
Autores principales: Montanucci, Ludovica, Fariselli, Piero, Martelli, Pier Luigi, Casadio, Rita
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718644/
https://www.ncbi.nlm.nih.gov/pubmed/18586713
http://dx.doi.org/10.1093/bioinformatics/btn166