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Predicting protein thermostability changes from sequence upon multiple mutations
Motivation: A basic question in protein science is to which extent mutations affect protein thermostability. This knowledge would be particularly relevant for engineering thermostable enzymes. In several experimental approaches, this issue has been serendipitously addressed. It would be therefore co...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718644/ https://www.ncbi.nlm.nih.gov/pubmed/18586713 http://dx.doi.org/10.1093/bioinformatics/btn166 |