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Efficient algorithms for accurate hierarchical clustering of huge datasets: tackling the entire protein space

Motivation: UPGMA (average linking) is probably the most popular algorithm for hierarchical data clustering, especially in computational biology. However, UPGMA requires the entire dissimilarity matrix in memory. Due to this prohibitive requirement, UPGMA is not scalable to very large datasets. Appl...

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Detalles Bibliográficos
Autores principales: Loewenstein, Yaniv, Portugaly, Elon, Fromer, Menachem, Linial, Michal
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718652/
https://www.ncbi.nlm.nih.gov/pubmed/18586742
http://dx.doi.org/10.1093/bioinformatics/btn174