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BLASTing small molecules—statistics and extreme statistics of chemical similarity scores

Motivation: Small organic molecules, from nucleotides and amino acids to metabolites and drugs, play a fundamental role in chemistry, biology and medicine. As databases of small molecules continue to grow and become more open, it is important to develop the tools to search them efficiently. In order...

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Detalles Bibliográficos
Autores principales: Baldi, Pierre, Benz, Ryan W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718662/
https://www.ncbi.nlm.nih.gov/pubmed/18586735
http://dx.doi.org/10.1093/bioinformatics/btn187