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The TCL1A Oncoprotein Interacts Directly with the NF-κB Inhibitor IκB
The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its pleckstrin homology (PH) domain. However, pertur...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718698/ https://www.ncbi.nlm.nih.gov/pubmed/19668332 http://dx.doi.org/10.1371/journal.pone.0006567 |