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Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis

Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249 SNPs. The most significant finding was for SNP rs121918...

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Detalles Bibliográficos
Autores principales: Feng, Bing-Jian, Sun, Liang-Dan, Soltani-Arabshahi, Razieh, Bowcock, Anne M., Nair, Rajan P., Stuart, Philip, Elder, James T., Schrodi, Steven J., Begovich, Ann B., Abecasis, Gonçalo R., Zhang, Xue-Jun, Callis-Duffin, Kristina P., Krueger, Gerald G., Goldgar, David E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718700/
https://www.ncbi.nlm.nih.gov/pubmed/19680446
http://dx.doi.org/10.1371/journal.pgen.1000606