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Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors
G-protein–coupled receptors (GPCRs) are generally thought to signal to second messengers like cyclic AMP (cAMP) from the cell surface and to become internalized upon repeated or prolonged stimulation. Once internalized, they are supposed to stop signaling to second messengers but may trigger nonclas...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718703/ https://www.ncbi.nlm.nih.gov/pubmed/19688034 http://dx.doi.org/10.1371/journal.pbio.1000172 |