Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

G-protein–coupled receptors (GPCRs) are generally thought to signal to second messengers like cyclic AMP (cAMP) from the cell surface and to become internalized upon repeated or prolonged stimulation. Once internalized, they are supposed to stop signaling to second messengers but may trigger nonclas...

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Detalles Bibliográficos
Autores principales: Calebiro, Davide, Nikolaev, Viacheslav O., Gagliani, Maria Cristina, de Filippis, Tiziana, Dees, Christian, Tacchetti, Carlo, Persani, Luca, Lohse, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718703/
https://www.ncbi.nlm.nih.gov/pubmed/19688034
http://dx.doi.org/10.1371/journal.pbio.1000172

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