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Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy

Proteolytic processing of the coronavirus replicase polyproteins is essential for ongoing viral ribonucleic acid (RNA) synthesis. Therefore, the severe acute respiratory syndrome (SARS)-coronaviruses (SARS-CoV) proteases are attractive targets for the development of antiviral drugs to reduce viral r...

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Detalles Bibliográficos
Autores principales: Ghosh, Arun K., Xi, Kai, Johnson, Michael E., Baker, Susan C., Mesecar, Andrew D.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718771/
https://www.ncbi.nlm.nih.gov/pubmed/19649165
http://dx.doi.org/10.1016/S0065-7743(06)41011-3