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Morphogenic and genetic differences between Candida albicans strains are associated with keratomycosis virulence

PURPOSE: To correlate the morphogenic and molecular traits that affect fungal virulence in human corneas. METHODS: C. albicans wild-type strains SC5314 and VE175 were compared using in vitro growth kinetics, filamentation assays, and microarray analysis. Corneal virulence was assessed ex vivo by ino...

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Detalles Bibliográficos
Autores principales: Hua, Xia, Yuan, Xiaoyong, Mitchell, Bradley M., Lorenz, Michael C., O’Day, Denis M., Wilhelmus, Kirk R.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718853/
https://www.ncbi.nlm.nih.gov/pubmed/19649176