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MMP7 Shedding of Syndecan-1 Facilitates Re-Epithelialization by Affecting α(2)β(1) Integrin Activation

BACKGROUND: Lung injury promotes the expression of matrix metalloproteinase-7 (MMP7, matrilysin), which is required for neutrophil recruitment and re-epithelialization. MMP7 governs the lung inflammatory response through the shedding of syndecan-1. Because inflammation and repair are related events,...

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Detalles Bibliográficos
Autores principales: Chen, Peter, Abacherli, Laura E., Nadler, Samuel T., Wang, Ying, Li, Qinglang, Parks, William C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719060/
https://www.ncbi.nlm.nih.gov/pubmed/19668337
http://dx.doi.org/10.1371/journal.pone.0006565