Amyloidogenic Regions and Interaction Surfaces Overlap in Globular Proteins Related to Conformational Diseases

Protein aggregation underlies a wide range of human disorders. The polypeptides involved in these pathologies might be intrinsically unstructured or display a defined 3D-structure. Little is known about how globular proteins aggregate into toxic assemblies under physiological conditions, where they...

Descripción completa

Detalles Bibliográficos
Autores principales: Castillo, Virginia, Ventura, Salvador
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719061/
https://www.ncbi.nlm.nih.gov/pubmed/19696882
http://dx.doi.org/10.1371/journal.pcbi.1000476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719061/
https://www.ncbi.nlm.nih.gov/pubmed/19696882
http://dx.doi.org/10.1371/journal.pcbi.1000476

Ejemplares similares