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Homeodomain Interacting Protein Kinase 2 Activation Compromises Endothelial Cell Response to Laminar Flow: Protective Role of p21(waf1,cip1,sdi1)

BACKGROUND: In the cardiovascular system, laminar shear stress (SS) is one of the most important source of endothelial protecting signals. Physical and chemical agents, however, including ionising radiations and anticancer drugs, may injure endothelial cells determining an increase in oxidative stre...

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Detalles Bibliográficos
Autores principales: Mattiussi, Stefania, Lazzari, Chiara, Truffa, Silvia, Antonini, Annalisa, Soddu, Silvia, Capogrossi, Maurizio C., Gaetano, Carlo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719102/
https://www.ncbi.nlm.nih.gov/pubmed/19668373
http://dx.doi.org/10.1371/journal.pone.0006603