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Homeodomain Interacting Protein Kinase 2 Activation Compromises Endothelial Cell Response to Laminar Flow: Protective Role of p21(waf1,cip1,sdi1)
BACKGROUND: In the cardiovascular system, laminar shear stress (SS) is one of the most important source of endothelial protecting signals. Physical and chemical agents, however, including ionising radiations and anticancer drugs, may injure endothelial cells determining an increase in oxidative stre...
Autores principales: | Mattiussi, Stefania, Lazzari, Chiara, Truffa, Silvia, Antonini, Annalisa, Soddu, Silvia, Capogrossi, Maurizio C., Gaetano, Carlo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719102/ https://www.ncbi.nlm.nih.gov/pubmed/19668373 http://dx.doi.org/10.1371/journal.pone.0006603 |
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